Your body is losing the one molecule it can't live without.
That fatigue, that blood pressure, that feeling that something shifted -- this is why.
8 clicks. Under 2 minutes. No blood draw.
Nitric oxide controls your blood pressure, your energy, your circulation, and how fast you age. Production drops 10-12% every decade. By 40, half is gone. Most people have no idea until something breaks.
Dr. Nathan S. Bryan — 25+ years of NO research · 100+ peer-reviewed publications · 5 books · Dozens of issued US and international patents
Research Published In
Nature Chemical BiologyPNASCirculationHypertensionFree Radical Biology & Medicine
How It Works
Science, not guesswork
01
Answer 8 Quick Questions
Your age, how you move, what you eat, how you sleep. No blood test. No lab visit. Under 2 minutes.
02
Your Body Gets Simulated
Your answers feed a model that simulates how nitric oxide moves through your blood, your tissues, and your red blood cells. The same science used in clinical trials.
03
See Exactly Where You Stand
Your NO Score, your cardiovascular age vs. your real age, which pathways are failing, and what to do about each one.
"By age 40, we have lost about 50% of our ability to produce nitric oxide in our blood vessels."
Dr. Nathan Bryan — Diary of a CEO, April 2025
Your NO Pathway
Age10-12%/decade
ExerciseHambrecht '03
DietKapil '10
Oral BacteriaTribble '19
VascularBryan '06
SleepEverson '05
Stress
MedicationsBryan '18
In His Own Words
The first sign and symptom of nitric oxide deficiency is usually erectile dysfunction. We call that the canary in the coal mine.
Dr. Nathan Bryan
Diary of a CEO
If you use mouthwash, within seven days your blood pressure goes up.
Dr. Nathan Bryan
Diary of a CEO, 2025
Nitric oxide is the master signal that tells blood vessels to open, mitochondria to produce energy, and the brain to function at full capacity.
Dr. Nathan Bryan
Deep Wealth Podcast
Without nitric oxide, your body cannot heal.
Dr. Nathan Bryan
Myers Detox Podcast
If you use mouthwash, you lose the cardioprotective benefits of exercise.
Dr. Nathan Bryan
Diary of a CEO, 2025
93% of Americans are metabolically unfit.
Dr. Nathan Bryan
Deep Wealth Podcast
I'm 51, but my vascular age is 36.
Dr. Nathan Bryan
American Muslim Today
If you're killing your oral microbiome and blocking stomach acid, your body can't make nitric oxide -- no matter how healthy your diet is.
Dr. Nathan Bryan
American Muslim Today
🧬
Analyzing Your NO Pathways
Mapping lifestyle inputs to physiology...
Running 3-compartment PK simulation...
Calculating pathway scores...
Generating recommendations...
Your Results
--
NO Score
Evidence-Based Recommendations
Track Your Progress
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Important: These statements have not been evaluated by the FDA. This assessment is educational, not medical advice. N1O1 products are not intended to diagnose, treat, cure, or prevent any disease.